People With Kidney Problems
This is perhaps the most important consideration.
Healthy kidneys help remove excess magnesium from the body through urine. But when kidney function is impaired, the body may have more difficulty getting rid of excess magnesium.
That means magnesium from supplements or certain medications can potentially build up in the bloodstream.
According to the NIH, the risk of magnesium toxicity increases when kidney function is impaired or when kidney failure is present.
For that reason, people with kidney disease should not simply start taking a high-dose magnesium